Photodiagnosis Photodyn Ther 2014 11: 7-12.ĭe Carvalho N, Schuh S, Kindermann N, Kästle R, Holmes J, Welzel J. Optical coherence tomography imaging of non-melanoma skin cancer undergoing photodynamic therapy reveals subclinical residual lesions. Themstrup L, Banzhaf CA, Mogensen M, Jemec GB. In vivo differentiation of common basal cell carcinoma subtypes by microvascular and structural imaging using dynamic optical coherence tomography. Themstrup L, De Carvalho N, Nielsen SM, Olsen J, Ciardo S, Schuh S, et al. The value of ultrahigh resolution OCT in dermatology - delineating the dermo-epidermal junction, capillaries in the dermal papillae and vellus hairs. Israelsen NM, Maria M, Mogensen M, Bojesen S, Jensen M, Haedersdal M, et al. Optical coherence tomography for presurgical margin assessment of non-melanoma skin cancer - a practical approach. JAMA Dermatol 2018 154: 1175-1183.Īlawi SA, Kuck M, Wahrlich C, Batz S, McKenzie G, Fluhr JW, et al. Evaluation of a combined reflectance confocal microscopy-optical coherence tomography device for detection and depth assessment of basal cell carcinoma. Sahu A, Yélamos O, Iftimia N, Cordova M, Alessi-Fox C, Gill M, et al. Using Reflectance confocal microscopy in skin cancer diagnosis. Preoperative measurement of thickness of cutaneous melanoma using high-resolution 20 MHz ultrasound imaging: a monocenter prospective study and systematic review of the literature. Machet L, Belot V, Naouri M, Boka M, Mourtada Y, Giraudeau B, et al. Pre-surgical high resolution ultrasound of facial basal cell carcinoma: correlation with histology. J Eur Acad Dermatol Venereol 2018 32: 1278-1283.īobadilla F, Wortsman X, Muñoz C, Segovia L, Espinoza M, Jemec GB. Interrater and intrarater agreement of confocal microscopy imaging in diagnosing and subtyping basal cell carcinoma. Kadouch DJ, van Haersma de With ASE, Elshot YS, Peppelman M, Bekkenk MW, Wolkerstorfer A, et al. Optical coherence tomography for diagnosis of basal cell carcinoma: essentials and perspectives. Comparison of different optical coherence tomography devices for diagnosis of non-melanoma skin cancer. Diagnosis of nonmelanoma skin cancer/keratinocyte carcinoma: a review of diagnostic accuracy of nonmelanoma skin cancer diagnostic tests and technologies. Instruments and new technologies for the in vivo diagnosis of melanoma. Marghoob AA, Swindle LD, Moricz CZ, Sanchez Negron FA, Slue B, Halpern AC, et al. Clinical performance of the Nevisense system in cutaneous melanoma detection: an international, multicentre, prospective and blinded clinical trial on efficacy and safety. Malvehy J, Hauschild A, Curiel-Lewandrowski C, Mohr P, Hofmann-Wellenhof R, Motley R, et al. Use of noninvasive imaging in the management of skin cancer. Giuffrida R, Conforti C, Di Meo N, Deinlein T, Guida S, Zalaudek I. Combining these advanced techniques may enable more efficient diagnosis of skin cancer. In conclusion, optical coherence tomography, reflectance confocal microscopy and photoacoustic imaging in combination enable image-guided bedside evaluation of suspicious pigmented skin tumours. No significant features were found in high-frequency ultrasound. Three novel photoacoustic imaging features, 7 reflectance confocal microscopy features, and 2 optical coherence tomography features were detected that had a high correlation with malignancy diagnostic accuracy > 71%. Morphological features and blood vessel characteristics were analysed with reflectance confocal microscopy, optical coherence tomography, high-frequency ultrasound and photoacoustic imaging images, and the diagnostic accuracy was assessed. A total of 41 pigmented skin tumours were scanned prior to excision. This pilot study evaluated the ability of optical coherence tomography, reflectance confocal microscopy, photo-acoustic imaging and high-frequency ultrasound to differentiate malignant from benign pigmented skin lesions. Combining imaging methods is therefore highly relevant for skin cancer diagnostics. Rapid diagnosis of suspicious pigmented skin lesions is imperative however, current bedside skin imaging technologies are either limited in penetration depth or resolution. Department of Dermatology, Copenhagen University Hospital, Bispebjerg and Frederiksberg, Nielsine Nielsens Vej 17, DK-2400 Copenhagen, Denmarkĭiagnostic imaging, pigmented skin neoplasm, photoacoustic techniques, confocal microscopy, optical coherence tomography, angiography Abstract
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