![]() Sutureless functional end-to-end anastomosis using the Endo GIA™ Reinforced appears to be safe, efficacious, and straightforward. No adhesive intestinal obstruction was noted. In the clinical population, no postoperative complications were noted. Small intestine anastomoses in the animal study exhibited no weakness at the crotch of the anastomosis, as tested with a probe, suggesting an increased resiliency to conventional complications of functional end-to-end anastomosis. In all cases, functional end-to-end anastomosis was performed without suture reinforcement. Furthermore, we performed functional end-to-end anastomosis using the Endo GIA™ Reinforced stapler in a clinical series of 20 patients undergoing gastrointestinal tract resection. As the crotch of the anastomosis is considered the weakest point, a probe was used to test the integrity of these anastomoses. A porcine model was used to examine functional end-to-end anastomosis with and without application of a bioabsorbable polyglycolic acid sheet. This study examined the clinical application of functional end-to-end anastomosis with a stapler that automatically applies a bioabsorbable polyglycolic acid sheet (Endo GIA™ Reinforced Reload with Tri-Staple™ Technology). Therefore, there is a requirement for new techniques that facilitate safe and efficacious anastomotic procedures. ![]() Functional end-to-end anastomosis, whilst extremely efficient, is vulnerable to increased intestinal pressure in the immediate postoperative period, which may predispose to development of anastomotic leakage or bleeding. Gastrointestinal anastomosis remains associated with a considerable burden of morbidity and, in some cases, mortality.
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